The Indus Dictionary Project
This symbol is a combination of the noun road and the verb to obscure. It means that it is difficult or impossible to see the road.
Lothal: Seal: L-48 a: Jagat Pati Joshi and Asko Parpola, 1987: Corpus of Indus Seals and Inscriptions: Volume 1: Page 249: Collections in India: Suomalainen Tiedeakatemia.
The translation will depend upon the context, when it might be more appropriate to substitute route or way for the noun road.
Indus Script Sign Number 141: Sign List of the Indus Script: Iravatham Mahadevan, 1977: The Indus Script: Texts, Concordance and Tables: The Director General Archaeological Survey of India.